Wonil Kim

Chief Scientific Officer Aston Sci

Wonil Kim, Ph.D., is Chief Scientific Officer at Aston Sci., Inc., where he leads the development of next-generation mRNA-based cancer vaccines using the proprietary AI-driven Th-Vac® platform. His work focuses on designing immunotherapies that activate robust CD4+ T cell responses through MHC class II-restricted epitopes, enabling effective and durable anti-tumor immunity. He is currently advancing multiple pipeline programs, including mRNA vaccine candidates targeting shared tumor antigens and neoantigens.
Dr. Kim has over 20 years of experience in oncology research, immunology, and drug development. He earned his Ph.D. from the University of Minnesota and completed postdoctoral training at Harvard Medical School and the Frederick National Laboratory for Cancer Research (NIH). He previously served as a Staff Scientist at St. Jude Children’s Research Hospital and held leadership roles at GeneOne Life Science and Cyrus Therapeutics. His expertise spans nucleotide-based therapeutics, translational research, and strategic R&D leadership in the biopharmaceutical industry.

Seminars

Wednesday 11th November 2026
Roundtable Discussion – Challenges & Solutions to Personalized Cancer Immunotherapy From Design to Manufacture
3:00 pm
  • Overcoming the challenges of small-scale GMP manufacturing capability on CMO/CDMO services for the personalized cancer vaccine, contributing to the increase in cost of manufacturing
  • Harmonizing the regulatory guidelines around the personalized cancer vaccine
  • Discussing the potential marketability of the personalized cancer vaccines in the future
Wednesday 11th November 2026
AI-Driven mRNA Cancer Vaccines: Precision Antigen Design & CD4⁺T-Cell Mediated Adaptive Immunity for Solid Tumors
2:30 pm
  • Engineering AI-driven mRNA cancer vaccines using the Th-Vac® platform to enable precision antigen selection and potent MHC class II–restricted CD4⁺T-cell activation in solid tumors
  • Integrating a multi-epitope design strategy that coordinates CD4⁺ T helper and CD8⁺ cytotoxic T-cell responses, establishing a “helper-killer axis” for amplified and sustained anti-tumor immunity
  • Advancing a differentiated immunotherapy paradigm that overcomes the resistance limitations of conventionally targeted therapies by inducing durable, adaptive immune responses against clinically relevant tumor antigens
Wonil Kim - Expert Speaker - 2nd RNA-Based Therapeutics & Vaccines South Korea